Varaico: Literature-Extracted Genetic Variants

LATS1

253 papers

RefSeq Summary

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is pho...

Pfam Domains

UBAaa 101–138UCSCUBA/TS-N domain

Pkinaseaa 705–866UCSCProtein kinase domain

Pkinaseaa 896–1010UCSCProtein kinase domain

Pkinase_Caa 1030–1080UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

large tumor suppressor kinase 1

HGNC Alias Symbol

WARTS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004690.4

p.R627M

c.1880G>T

Surrounding Variants

1 paper

NM_004690.4

p.R627S

c.1881G>T

1 paper

NM_004690.4

p.R627S

c.1881G>C

1 paper

NM_004690.4

p.R627W

c.1879A>T

1 paper

NM_004690.4

p.R626Q

c.1877G>A

1 paper

NM_004690.4

p.R630H

c.1889G>A

1 paper

NM_004690.4

p.D623H

c.1867G>C

1 paper

NM_004690.4

p.Q632K

c.1894C>A

1 paper

NM_004690.4

p.N620K

c.1860C>G

1 paper

NM_004690.4

p.N620K

c.1860C>A

1 paper

NM_004690.4

p.I615T

c.1844T>C

3 papers

NM_004690.4

p.F641L

c.1921T>C

3 papers

NM_004690.4

p.F641L

c.1923C>G