Varaico: Literature-Extracted Genetic Variants

LATS1

253 papers

RefSeq Summary

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is pho...

Pfam Domains

UBAaa 101–138UCSCUBA/TS-N domain

Pkinaseaa 705–866UCSCProtein kinase domain

Pkinaseaa 896–1010UCSCProtein kinase domain

Pkinase_Caa 1030–1080UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

large tumor suppressor kinase 1

HGNC Alias Symbol

WARTS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004690.4

p.E598D

c.1794A>T

Surrounding Variants

1 paper

NM_004690.4

p.E598D

c.1794A>C

1 paper

NM_004690.4

p.S596R

c.1788T>G

1 paper

NM_004690.4

p.S596R

c.1788T>A

1 paper

NM_004690.4

p.S596R

c.1786A>C

1 paper

NM_004690.4

p.K595N

c.1785G>T

1 paper

NM_004690.4

p.K595N

c.1785G>C

1 paper

NM_004690.4

p.G603R

c.1807G>C

1 paper

NM_004690.4

p.G603R

c.1807G>A

1 paper

NM_004690.4

p.E594K

c.1780G>A

1 paper

NM_004690.4

p.S593N

c.1778G>A

2 papers

NM_004690.4

p.E606G

c.1817A>G

2 papers

NM_004690.4

p.K607N

c.1821G>T