Varaico: Literature-Extracted Genetic Variants

LATS1

253 papers

RefSeq Summary

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is pho...

Pfam Domains

UBAaa 101–138UCSCUBA/TS-N domain

Pkinaseaa 705–866UCSCProtein kinase domain

Pkinaseaa 896–1010UCSCProtein kinase domain

Pkinase_Caa 1030–1080UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

large tumor suppressor kinase 1

HGNC Alias Symbol

WARTS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_004690.4

p.R502C

c.1504C>T

Surrounding Variants

2 papers

NM_004690.4

p.P506R

c.1517C>G

1 paper

NM_004690.4

p.Q495R

c.1484A>G

2 papers

NM_004690.4

p.P493S

c.1477C>T

1 paper

NM_004690.4

p.T487A

c.1459A>G

1 paper

NM_004690.4

p.P517L

c.1550C>T

1 paper

NM_004690.4

p.P517H

c.1550C>A

1 paper

NM_004690.4

p.W519R

c.1555T>C

1 paper

NM_004690.4

p.W519R

c.1555T>A

2 papers

NM_004690.4

p.W519C

c.1557G>T

2 papers

NM_004690.4

p.W519C

c.1557G>C

1 paper

NM_004690.4

p.T484A

c.1450A>G

3 papers

NM_004690.4

p.A483T

c.1447G>A