Varaico: Literature-Extracted Genetic Variants

LATS1

253 papers

RefSeq Summary

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is pho...

Pfam Domains

UBAaa 101–138UCSCUBA/TS-N domain

Pkinaseaa 705–866UCSCProtein kinase domain

Pkinaseaa 896–1010UCSCProtein kinase domain

Pkinase_Caa 1030–1080UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

large tumor suppressor kinase 1

HGNC Alias Symbol

WARTS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004690.4

p.S482S

c.1446T>C

Surrounding Variants

3 papers

NM_004690.4

p.A483T

c.1447G>A

1 paper

NM_004690.4

p.T484A

c.1450A>G

1 paper

NM_004690.4

p.P481S

c.1441C>T

1 paper

NM_004690.4

p.Q480*

c.1438C>T

1 paper

NM_004690.4

p.T487A

c.1459A>G

1 paper

NM_004690.4

p.S476F

c.1427C>T

3 papers

NM_001350392.2

p.H195Y

c.583C>T

NM_004690.4

p.H475Y

c.1423C>T

2 papers

NM_004690.4

p.P493S

c.1477C>T

4 papers

NM_004690.4

p.N471S

c.1412A>G

1 paper

NM_004690.4

p.G470E

c.1409G>A

1 paper

NM_004690.4

p.Q495R

c.1484A>G

2 papers

NM_004690.4

p.P468S

c.1402C>T