Varaico: Literature-Extracted Genetic Variants

LATS1

253 papers

RefSeq Summary

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is pho...

Pfam Domains

UBAaa 101–138UCSCUBA/TS-N domain

Pkinaseaa 705–866UCSCProtein kinase domain

Pkinaseaa 896–1010UCSCProtein kinase domain

Pkinase_Caa 1030–1080UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

large tumor suppressor kinase 1

HGNC Alias Symbol

WARTS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004690.4

p.V411M

c.1231G>A

Surrounding Variants

1 paper

NM_004690.4

p.V411A

c.1232T>C

1 paper

NM_004690.4

p.Q407*

c.1219C>T

2 papers

NM_004690.4

p.H417D

c.1249C>G

1 paper

NM_004690.4

p.G403E

c.1208G>A

2 papers

NM_004690.4

p.M419I

c.1257G>T

2 papers

NM_004690.4

p.M419I

c.1257G>C

2 papers

NM_004690.4

p.M419I

c.1257G>A

1 paper

NM_004690.4

p.I424M

c.1272T>G

1 paper

NM_004690.4

p.A396A

c.1188T>G

1 paper

NM_004690.4

p.S394C

c.1181C>G

1 paper

NM_004690.4

p.S394Y

c.1181C>A

1 paper

NM_004690.4

p.V426_G428del0

c.1277_1282del6