Varaico: Literature-Extracted Genetic Variants

LATS1

253 papers

RefSeq Summary

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is pho...

Pfam Domains

UBAaa 101–138UCSCUBA/TS-N domain

Pkinaseaa 705–866UCSCProtein kinase domain

Pkinaseaa 896–1010UCSCProtein kinase domain

Pkinase_Caa 1030–1080UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

large tumor suppressor kinase 1

HGNC Alias Symbol

WARTS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_004690.4

p.S336G

c.1006A>G

Surrounding Variants

1 paper

NM_004690.4

p.F340delFs

c.1020delA

1 paper

NM_004690.4

p.P341L

c.1022C>T

1 paper

NM_004690.4

p.P341fs

c.1021_1022fs

1 paper

NM_004690.4

p.S321T

c.962G>C

1 paper

NM_004690.4

p.Q315*

c.943C>T

1 paper

NM_004690.4

p.P313S

c.937C>T

1 paper

NM_004690.4

p.H359L

c.1076A>T

1 paper

NM_004690.4

p.H359P

c.1076A>C

1 paper

NM_004690.4

p.N361fs

c.1081_1082fs

1 paper

NM_004690.4

p.N311D

c.931A>G

1 paper

NM_004690.4

p.M310V

c.928A>G

1 paper

NM_004690.4

p.S308F

c.923C>T