Varaico: Literature-Extracted Genetic Variants

LATS1

253 papers

RefSeq Summary

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is pho...

Pfam Domains

UBAaa 101–138UCSCUBA/TS-N domain

Pkinaseaa 705–866UCSCProtein kinase domain

Pkinaseaa 896–1010UCSCProtein kinase domain

Pkinase_Caa 1030–1080UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

large tumor suppressor kinase 1

HGNC Alias Symbol

WARTS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004690.4

p.V284E

c.851T>A

Surrounding Variants

1 paper

NM_004690.4

p.V284I

c.850G>A

2 papers

NM_004690.4

p.R287*

c.859C>T

2 papers

NM_004690.4

p.R287Q

c.860G>A

1 paper

NM_004690.4

p.I288N

c.863T>A

2 papers

NM_004690.4

p.I288M

c.864C>G

1 paper

NM_004690.4

p.S289C

c.866C>G

3 papers

NM_004690.4

p.S278C

c.833C>G

3 papers

NM_004690.4

p.Y277C

c.830A>G

1 paper

NM_004690.4

p.P292L

c.875C>T

1 paper

NM_004690.4

p.R276C

c.826C>T

1 paper

NM_004690.4

p.P292fs

c.874_875fs

1 paper

NM_004690.4

p.T274I

c.821C>T