Varaico: Literature-Extracted Genetic Variants

LATS1

253 papers

RefSeq Summary

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is pho...

Pfam Domains

UBAaa 101–138UCSCUBA/TS-N domain

Pkinaseaa 705–866UCSCProtein kinase domain

Pkinaseaa 896–1010UCSCProtein kinase domain

Pkinase_Caa 1030–1080UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

large tumor suppressor kinase 1

HGNC Alias Symbol

WARTS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004690.4

p.P250L

c.749C>T

Surrounding Variants

2 papers

NM_004690.4

p.P250S

c.748C>T

1 paper

NM_004690.4

p.P250T

c.748C>A

1 paper

NM_004690.4

p.P251A

c.751C>G

2 papers

NM_004690.4

p.R252I

c.755G>T

1 paper

NM_004690.4

p.Q254H

c.762G>T

1 paper

NM_004690.4

p.Q254H

c.762G>C

2 papers

NM_004690.4

p.T255A

c.763A>G

1 paper

NM_004690.4

p.V245A

c.734T>C

1 paper

NM_004690.4

p.T255N

c.764C>A

1 paper

NM_004690.4

p.S244R

c.732T>G

1 paper

NM_004690.4

p.S244R

c.732T>A

1 paper

NM_004690.4

p.P256S

c.766C>T