Varaico: Literature-Extracted Genetic Variants

LATS1

253 papers

RefSeq Summary

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is pho...

Pfam Domains

UBAaa 101–138UCSCUBA/TS-N domain

Pkinaseaa 705–866UCSCProtein kinase domain

Pkinaseaa 896–1010UCSCProtein kinase domain

Pkinase_Caa 1030–1080UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

large tumor suppressor kinase 1

HGNC Alias Symbol

WARTS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004690.4

p.H227Q

c.681C>A

Surrounding Variants

1 paper

NM_004690.4

p.H227Q

c.681C>G

1 paper

NM_004690.4

p.S229G

c.685A>G

1 paper

NM_004690.4

p.A226P

c.676G>C

1 paper

NM_004690.4

p.Q225*

c.673C>T

1 paper

NM_004690.4

p.Q225E

c.673C>G

1 paper

NM_004690.4

p.G231*

c.691G>T

1 paper

NM_004690.4

p.Q232Q

c.696G>A

1 paper

NM_004690.4

p.A222V

c.665C>T

2 papers

NM_004690.4

p.R233S

c.699A>T

2 papers

NM_004690.4

p.R233S

c.699A>C

1 paper

NM_004690.4

p.V234L

c.700G>T

1 paper

NM_004690.4

p.V234L

c.700G>C