Varaico: Literature-Extracted Genetic Variants

LATS1

253 papers

RefSeq Summary

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is pho...

Pfam Domains

UBAaa 101–138UCSCUBA/TS-N domain

Pkinaseaa 705–866UCSCProtein kinase domain

Pkinaseaa 896–1010UCSCProtein kinase domain

Pkinase_Caa 1030–1080UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

large tumor suppressor kinase 1

HGNC Alias Symbol

WARTS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004690.4

p.W178*

c.534G>A

Surrounding Variants

1 paper

NM_004690.4

p.W178*

c.533G>A

1 paper

NM_004690.4

p.Q176L

c.527A>T

1 paper

NM_004690.4

p.Q176R

c.527A>G

1 paper

NM_004690.4

p.R174H

c.521G>A

1 paper

NM_004690.4

p.R174C

c.520C>T

1 paper

NM_004690.4

p.S184C

c.551C>G

1 paper

NM_004690.4

p.S171*

c.512C>G

1 paper

NM_004690.4

p.S171*

c.512C>A

1 paper

NM_004690.4

p.Q170*

c.508C>T

1 paper

NM_004690.4

p.Q170fs

c.508_509fs

1 paper

NM_004690.4

p.Q188R

c.563A>G

1 paper

NM_004690.4

p.R189T

c.566G>C