Varaico: Literature-Extracted Genetic Variants

LATS1

253 papers

RefSeq Summary

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is pho...

Pfam Domains

UBAaa 101–138UCSCUBA/TS-N domain

Pkinaseaa 705–866UCSCProtein kinase domain

Pkinaseaa 896–1010UCSCProtein kinase domain

Pkinase_Caa 1030–1080UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

large tumor suppressor kinase 1

HGNC Alias Symbol

WARTS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_004690.4

p.S94A

c.280T>G

Surrounding Variants

6 papers

NM_004690.4

p.R96W

c.286C>T

3 papers

NM_004690.4

p.R96Q

c.287G>A

1 paper

NM_004690.4

p.I81_A89delFs

c.242_266del25

1 paper

NM_004690.4

p.S99L

c.296C>T

1 paper

NM_004690.4

p.E100*

c.298G>T

1 paper

NM_004690.4

p.V101F

c.301G>T

1 paper

NM_004690.4

p.L86R

c.257T>G

1 paper

NM_004690.4

p.M105I

c.315G>T

1 paper

NM_004690.4

p.M105I

c.315G>C

1 paper

NM_004690.4

p.R82P

c.245G>C

2 papers

NM_004690.4

p.R82Q

c.245G>A

1 paper

NM_004690.4

p.M105I

c.315G>A