Varaico: Literature-Extracted Genetic Variants

LATS1

253 papers

RefSeq Summary

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is pho...

Pfam Domains

UBAaa 101–138UCSCUBA/TS-N domain

Pkinaseaa 705–866UCSCProtein kinase domain

Pkinaseaa 896–1010UCSCProtein kinase domain

Pkinase_Caa 1030–1080UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

large tumor suppressor kinase 1

HGNC Alias Symbol

WARTS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004690.4

p.A47S

c.139G>T

Surrounding Variants

1 paper

NM_004690.4

p.A47V

c.140C>T

1 paper

NM_004690.4

p.S45_D46Fs

c.134_136delinsCCFs

2 papers

NM_004690.4

p.S45Y

c.134C>A

2 papers

NM_004690.4

p.P44L

c.131C>T

1 paper

NM_004690.4

p.A50V

c.149C>T

1 paper

NM_004690.4

p.E51K

c.151G>A

1 paper

NM_004690.4

p.H52Y

c.154C>T

1 paper

NM_004690.4

p.K56fs

c.166_167fs

1 paper

NM_004690.4

p.M57V

c.169A>G

2 papers

NM_004690.4

p.E36D

c.108A>T

2 papers

NM_004690.4

p.E36D

c.108A>C

2 papers

NM_004690.4

p.R35W

c.103C>T