Varaico: Literature-Extracted Genetic Variants

LATS1

253 papers

RefSeq Summary

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is pho...

Pfam Domains

UBAaa 101–138UCSCUBA/TS-N domain

Pkinaseaa 705–866UCSCProtein kinase domain

Pkinaseaa 896–1010UCSCProtein kinase domain

Pkinase_Caa 1030–1080UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

large tumor suppressor kinase 1

HGNC Alias Symbol

WARTS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004690.4

p.R28W

c.82C>T

Surrounding Variants

2 papers

NM_004690.4

p.R28Q

c.83G>A

2 papers

NM_004690.4

p.S27R

c.79A>C

1 paper

NM_004690.4

p.V25D

c.74T>A

2 papers

NM_004690.4

p.V25F

c.73G>T

1 paper

NM_004690.4

p.S21fs

c.61_62fs

2 papers

NM_004690.4

p.R35W

c.103C>T

2 papers

NM_004690.4

p.E36D

c.108A>T

2 papers

NM_004690.4

p.E36D

c.108A>C

2 papers

NM_004690.4

p.T17T

c.51C>G

2 papers

NM_004690.4

p.P44L

c.131C>T

2 papers

NM_004690.4

p.R11G

c.31A>G

2 papers

NM_004690.4

p.S45Y

c.134C>A