Varaico: Literature-Extracted Genetic Variants

LATS2

273 papers

RefSeq Summary

This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts wi...

Pfam Domains

Pkinaseaa 668–830UCSCProtein kinase domain

Pkinaseaa 858–973UCSCProtein kinase domain

Pkinase_Caa 993–1042UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

large tumor suppressor kinase 2

HGNC Previous Names

LATS (large tumor suppressor, Drosophila) homolog 2; LATS, large tumor suppressor, homolog 2 (Drosophila)

Papers

RefSeq ID

Protein change

DNA change

1–12 of 564 variants

11 papers

NM_014572.3

p.A324V

c.971C>T

8 papers

NM_014572.3

p.A203V

c.608C>T

8 papers

NM_014572.3

p.G363S

c.1087G>A

5 papers

NM_014572.3

p.R958H

c.2873G>A

5 papers

NM_014572.3

p.T1041A

c.3121A>G

4 papers

NM_014572.3

p.R558H

c.1673G>A

4 papers

NM_014572.3

p.E1016K

c.3046G>A

3 papers

NM_014572.3

p.G40E

c.119G>A

3 papers

NM_014572.3

p.T168M

c.503C>T

3 papers

NM_014572.3

p.P190R

c.569C>G

3 papers

NM_014572.3

p.G268A

c.803G>C

3 papers

NM_014572.3

p.P551L

c.1652C>T