Varaico: Literature-Extracted Genetic Variants

Gene:LCP2
Variant:p.I427V

LCP2

138 papers

RefSeq Summary

This gene encodes an adapter protein that acts as a substrate of the T cell antigen receptor (TCR)-activated protein tyrosine kinase pathway. The encoded protein associates with growth factor receptor...

Pfam Domains

SAM_2aa 12–76UCSCSAM domain (Sterile alpha motif)
SH2aa 422–505UCSCSH2 domain

Gene Aliases

HGNC Name

lymphocyte cytosolic protein 2

HGNC Previous Symbol

SLP76

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005565.5
p.I427V
c.1279A>G
Surrounding Variants
1 paper
NM_005565.5
p.T428I
c.1283C>T
1 paper
NM_005565.5
p.W422C
c.1266G>T
1 paper
NM_005565.5
p.W422C
c.1266G>C
1 paper
NM_005565.5
p.A434V
c.1301C>T
1 paper
NM_005565.5
p.A412T
c.1234G>A
1 paper
NM_005565.5
p.S410S
c.1230C>T
1 paper
NM_005565.5
p.S410F
c.1229C>T
4 papers
NM_005565.5
p.S410C
c.1229C>G
1 paper
NM_005565.5
p.P409R
c.1226C>G
1 paper
NM_005565.5
p.R448K
c.1343G>A
1 paper
NM_005565.5
p.D449H
c.1345G>C
1 paper
NM_005565.5
p.S450N
c.1349G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."