Varaico: Literature-Extracted Genetic Variants

Gene:LDHA
Variant:p.Q66R

LDHA

160 papers

RefSeq Summary

This gene encodes the A subunit of lactate dehydrogenase enzyme which catalyzes the reversible conversion of pyruvate to lactate with the concomitant oxidation of NADH to NAD in anaerobic glycolysis. ...

Pfam Domains

Ldh_1_Naa 21–160UCSClactate/malate dehydrogenase, NAD binding domain
Ldh_1_Caa 163–331UCSClactate/malate dehydrogenase, alpha/beta C-terminal domain

Gene Aliases

HGNC Name

lactate dehydrogenase A

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005566.4
p.Q66R
c.197A>G
Surrounding Variants
1 paper
NM_005566.4
p.L65I
c.193C>A
1 paper
NM_005566.4
p.G68D
c.203G>A
1 paper
NM_005566.4
p.L70F
c.208C>T
1 paper
NM_005566.4
p.M62K
c.185T>A
1 paper
NM_005566.4
p.R73G
c.217A>G
1 paper
NM_005566.4
p.E55K
c.163G>A
1 paper
NM_005566.4
p.V78I
c.232G>A
1 paper
NM_005566.4
p.S79A
c.235T>G
1 paper
NM_005566.4
p.V53G
c.158T>G
1 paper
NM_005566.4
p.V51G
c.152T>G
2 papers
NM_005566.4
p.D82N
c.244G>A
1 paper
NM_005566.4
p.A49T
c.145G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."