Varaico: Literature-Extracted Genetic Variants

Gene:LDHB
Variant:p.W325R

LDHB

78 papers

RefSeq Summary

This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis proc...

Pfam Domains

Ldh_1_Naa 22–161UCSClactate/malate dehydrogenase, NAD binding domain
Ldh_1_Caa 164–334UCSClactate/malate dehydrogenase, alpha/beta C-terminal domain

Gene Aliases

HGNC Name

lactate dehydrogenase B

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_002300.8
p.W325R
c.973T>A
Surrounding Variants
3 papers
NM_002300.8
p.W325R
c.973T>C
1 paper
NM_002300.8
p.W325*
c.974G>A
1 paper
NM_002300.8
p.W325*
c.975G>A
1 paper
NM_002300.8
p.D326N
c.976G>A
1 paper
NM_002300.8
p.D322V
c.965A>T
1 paper
NM_002300.8
p.K318N
c.954G>T
1 paper
NM_002300.8
p.K318N
c.954G>C
1 paper
NM_002300.8
p.D333Y
c.997G>T
1 paper
NM_002300.8
p.K310R
c.929A>G
1 paper
NM_002300.8
p.Q307Q
c.921G>A
1 paper
NM_002300.8
p.V304I
c.910G>A
1 paper
NM_002300.8
p.G300E
c.899G>A
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