Varaico: Literature-Extracted Genetic Variants

LEF1

243 papers

RefSeq Summary

This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally impor...

Pfam Domains

CTNNB1_bindingaa 9–213UCSCN-terminal CTNNB1 binding

HMG_boxaa 299–367UCSCHMG (high mobility group) box

Gene Aliases

HGNC Name

lymphoid enhancer binding factor 1

HGNC Alias Symbols

TCF1ALPHA; TCF10; TCF7L3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_016269.5

p.E325Fs

c.975delinsGGAAGGFs

Surrounding Variants

1 paper

NM_016269.5

p.S326fs

c.976_977fs

1 paper

NM_016269.5

p.K324ins3

c.970_971ins9

1 paper

NM_016269.5

p.T322A

c.964A>G

1 paper

NM_016269.5

p.C321Y

c.962G>A

1 paper

NM_016269.5

p.N330S

c.989A>G

1 paper

NM_016269.5

p.I332S

c.995T>G

3 papers

NM_016269.5

p.V318insFs

c.952_953ins5

3 papers

NM_016269.5

p.V318fs

c.952_953fs

1 paper

NM_016269.5

p.V318F

c.952G>T

1 paper

NM_016269.5

p.V317A

c.950T>C

1 paper

NM_016269.5

p.G334D

c.1001G>A

1 paper

NM_016269.5

p.R335R

c.1005A>G