Varaico: Literature-Extracted Genetic Variants

LEF1

243 papers

RefSeq Summary

This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally impor...

Pfam Domains

CTNNB1_bindingaa 9–213UCSCN-terminal CTNNB1 binding

HMG_boxaa 299–367UCSCHMG (high mobility group) box

Gene Aliases

HGNC Name

lymphoid enhancer binding factor 1

HGNC Alias Symbols

TCF1ALPHA; TCF10; TCF7L3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_016269.5

p.H96insFs

c.287_288insC

Surrounding Variants

1 paper

NM_016269.5

p.K95N

c.285G>T

1 paper

NM_016269.5

p.K95N

c.285G>C

1 paper

NM_016269.5

p.G94E

c.281G>A

2 papers

NM_016269.5

p.L101P

c.302T>C

1 paper

NM_016269.5

p.K104K

c.312G>A

1 paper

NM_016269.5

p.N103_K104del1

c.309_311delTTG

1 paper

NM_016269.5

p.G105*

c.313G>T

1 paper

NM_016269.5

p.N103_K104del2

c.307_311del6

6 papers

NM_016269.5

p.P106L

c.317C>T

2 papers

NM_016269.5

p.P106P

c.318C>T

1 paper

NM_016269.5

p.S107insFs

c.319_320insT

1 paper

NM_016269.5

p.S112A

c.334T>G