Varaico: Literature-Extracted Genetic Variants

LEF1

243 papers

RefSeq Summary

This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally impor...

Pfam Domains

CTNNB1_bindingaa 9–213UCSCN-terminal CTNNB1 binding

HMG_boxaa 299–367UCSCHMG (high mobility group) box

Gene Aliases

HGNC Name

lymphoid enhancer binding factor 1

HGNC Alias Symbols

TCF1ALPHA; TCF10; TCF7L3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_016269.5

p.S61P

c.181T>C

Surrounding Variants

1 paper

NM_016269.5

p.I64V

c.190A>G

1 paper

NM_016269.5

p.K54E

c.160A>G

1 paper

NM_016269.5

p.I53I

c.159C>T

1 paper

NM_016269.5

p.N68S

c.203A>G

1 paper

NM_016269.5

p.G69A

c.206G>C

1 paper

NM_016269.5

p.H70D

c.208C>G

2 papers

NM_016269.5

p.A51T

c.151G>A

1 paper

NM_016269.5

p.P44_E45delFs

c.131_134del4

2 papers

NM_016269.5

p.E45K

c.133G>A

1 paper

NM_016269.5

p.I41V

c.121A>G

1 paper

NM_016269.5

p.E40A

c.119A>C

1 paper

NM_016269.5

p.E40K

c.118G>A