Varaico: Literature-Extracted Genetic Variants

LEF1

243 papers

RefSeq Summary

This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally impor...

Pfam Domains

CTNNB1_bindingaa 9–213UCSCN-terminal CTNNB1 binding

HMG_boxaa 299–367UCSCHMG (high mobility group) box

Gene Aliases

HGNC Name

lymphoid enhancer binding factor 1

HGNC Alias Symbols

TCF1ALPHA; TCF10; TCF7L3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_016269.5

p.D14fs

c.40_41fs

Surrounding Variants

1 paper

NM_016269.5

p.D14insFs

c.40dupG

1 paper

NM_016269.5

p.D14delFs

c.40delC

1 paper

NM_016269.5

p.G12G

c.36G>C

1 paper

NM_016269.5

p.G12A

c.35G>C

1 paper

NM_016269.5

p.E16*

c.46G>T

1 paper

NM_016269.5

p.G12R

c.34G>C

1 paper

NM_016269.5

p.G12R

c.34G>A

1 paper

NM_016269.5

p.G11G

c.33C>G

1 paper

NM_016269.5

p.A19D

c.56C>A

1 paper

NM_016269.5

p.A19A

c.57C>T

1 paper

NM_016269.5

p.E22K

c.64G>A

1 paper

NM_016269.5

p.M23I

c.69G>T