Varaico: Literature-Extracted Genetic Variants

LEFTY2

53 papers

RefSeq Summary

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activat...

Pfam Domains

TGFb_propeptideaa 79–225UCSCTGF-beta propeptide

TGF_betaaa 262–353UCSCTransforming growth factor beta like domain

Gene Aliases

HGNC Name

left-right determination factor 2

HGNC Previous Symbols

TGFB4; EBAF

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003240.5

p.K279E

c.835A>G

Surrounding Variants

1 paper

NM_003240.5

p.P286L

c.857C>T

1 paper

NM_003240.5

p.E267K

c.799G>A

1 paper

NM_003240.5

p.R265H

c.794G>A

1 paper

NM_003240.5

p.V294M

c.880G>A

1 paper

NM_003240.5

p.C297F

c.890G>T

1 paper

NM_003240.5

p.Q298R

c.893A>G

1 paper

NM_003240.5

p.Q298H

c.894G>T

1 paper

NM_003240.5

p.T258T

c.774C>T

1 paper

NM_003240.5

p.P309T

c.925C>A

5 papers

NM_003240.5

p.R314*

c.940C>T

1 paper

NM_003240.5

p.A318T

c.952G>A

2 papers

NM_003240.5

p.V328I

c.982G>A