Varaico: Literature-Extracted Genetic Variants

LEFTY2

53 papers

RefSeq Summary

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activat...

Pfam Domains

TGFb_propeptideaa 79–225UCSCTGF-beta propeptide

TGF_betaaa 262–353UCSCTransforming growth factor beta like domain

Gene Aliases

HGNC Name

left-right determination factor 2

HGNC Previous Symbols

TGFB4; EBAF

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003240.5

p.H171insFs

c.512_513insGC

Surrounding Variants

1 paper

NM_003240.5

p.R166W

c.496A>T

1 paper

NM_003240.5

p.Q188*

c.562C>T

1 paper

NM_003240.5

p.R192R

c.576G>A

1 paper

NM_003240.5

p.A226A

c.678G>A

1 paper

NM_003240.5

p.A226_P227del2

c.676_680del6

1 paper

NM_003240.5

p.P233P

c.699C>G

1 paper

NM_003240.5

p.N158N

c.474C>T

1 paper

NM_003240.5

p.L235delFs

c.705delC

1 paper

NM_003240.5

p.R153R

c.459C>T

1 paper

NM_003240.5

p.P138P

c.414G>A

1 paper

NM_003240.5

p.V117M

c.349G>A

1 paper

NM_003240.5

p.N110N

c.330C>T