Varaico: Literature-Extracted Genetic Variants

LEFTY2

53 papers

RefSeq Summary

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activat...

Pfam Domains

TGFb_propeptideaa 79–225UCSCTGF-beta propeptide

TGF_betaaa 262–353UCSCTransforming growth factor beta like domain

Gene Aliases

HGNC Name

left-right determination factor 2

HGNC Previous Symbols

TGFB4; EBAF

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003240.5

p.K76delFs

c.226_227delTT

Surrounding Variants

1 paper

NM_003240.5

p.K76fs

c.226_227fs

1 paper

NM_003240.5

p.R74R

c.222C>A

1 paper

NM_003240.5

p.R72C

c.214C>T

1 paper

NM_003240.5

p.R83G

c.247C>G

1 paper

NM_003240.5

p.H69D

c.205C>G

1 paper

NM_003240.5

p.V57M

c.169G>A

1 paper

NM_003240.5

p.A55T

c.163G>A

1 paper

NM_003240.5

p.P41L

c.122C>T

1 paper

NM_003240.5

p.A20V

c.59C>T

1 paper

NM_003240.5

p.W2_P3insT

c.4_8ins3

1 paper

NM_003240.5

p.M1insFs

c.2_3insT

1 paper

NM_003240.5

p.E104E

c.312G>A