Varaico: Literature-Extracted Genetic Variants

Gene:LEP
Variant:p.T71T

LEP

798 papers

RefSeq Summary

This gene encodes a protein that is secreted by white adipocytes into the circulation and plays a major role in the regulation of energy homeostasis. Circulating leptin binds to the leptin receptor in...

Pfam Domains

Leptinaa 23–167UCSCLeptin

Gene Aliases

HGNC Name

leptin

HGNC Previous Symbols

OBS; OB

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_000230.3
p.T71T
c.213C>T
Surrounding Variants
1 paper
NM_000230.3
p.T71N
c.212C>A
1 paper
NM_000230.3
p.L72I
c.214T>A
1 paper
NM_000230.3
p.L72V
c.214T>G
2 papers
NM_000230.3
p.T71A
c.211A>G
1 paper
NM_000230.3
p.T71S
c.211A>T
1 paper
NM_000230.3
p.L72*
c.215T>A
29 papers
NM_000230.3
p.L72S
c.215T>C
1 paper
NM_000230.3
p.S73P
c.217T>C
1 paper
NM_000230.3
p.S73F
c.218C>T
2 papers
NM_000230.3
p.I69M
c.207C>G
2 papers
NM_000230.3
p.I69I
c.207C>T
2 papers
NM_000230.3
p.I69T
c.206T>C
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