Varaico: Literature-Extracted Genetic Variants

Gene:LEP
Variant:p.T87N

LEP

798 papers

RefSeq Summary

This gene encodes a protein that is secreted by white adipocytes into the circulation and plays a major role in the regulation of energy homeostasis. Circulating leptin binds to the leptin receptor in...

Pfam Domains

Leptinaa 23–167UCSCLeptin

Gene Aliases

HGNC Name

leptin

HGNC Previous Symbols

OBS; OB

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_000230.3
p.T87N
c.260C>A
Surrounding Variants
1 paper
NM_000230.3
p.T87T
c.261C>A
2 papers
NM_000230.3
p.S88C
c.262A>T
1 paper
NM_000230.3
p.S88N
c.263G>A
1 paper
NM_000230.3
p.L86F
c.256C>T
1 paper
NM_000230.3
p.S88R
c.264T>A
1 paper
NM_000230.3
p.M89V
c.265A>G
1 paper
NM_000230.3
p.M89L
c.265A>T
1 paper
NM_000230.3
p.I85M
c.255C>G
1 paper
NM_000230.3
p.I85I
c.255C>T
1 paper
NM_000230.3
p.I85V
c.253A>G
1 paper
NM_000230.3
p.I85F
c.253A>T
1 paper
NM_000230.3
p.M89I
c.267G>T
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