Varaico: Literature-Extracted Genetic Variants

Gene:LEP
Variant:p.M89I

LEP

798 papers

RefSeq Summary

This gene encodes a protein that is secreted by white adipocytes into the circulation and plays a major role in the regulation of energy homeostasis. Circulating leptin binds to the leptin receptor in...

Pfam Domains

Leptinaa 23–167UCSCLeptin

Gene Aliases

HGNC Name

leptin

HGNC Previous Symbols

OBS; OB

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000230.3
p.M89I
c.267G>T
Surrounding Variants
1 paper
NM_000230.3
p.P90delFs
c.268delC
1 paper
NM_000230.3
p.P90T
c.268C>A
1 paper
NM_000230.3
p.M89V
c.265A>G
1 paper
NM_000230.3
p.M89L
c.265A>T
1 paper
NM_000230.3
p.P90R
c.269C>G
1 paper
NM_000230.3
p.S88R
c.264T>A
1 paper
NM_000230.3
p.S88N
c.263G>A
2 papers
NM_000230.3
p.S88C
c.262A>T
1 paper
NM_000230.3
p.T87T
c.261C>A
2 papers
NM_000230.3
p.T87N
c.260C>A
1 paper
NM_000230.3
p.N93D
c.277A>G
1 paper
NM_000230.3
p.L86F
c.256C>T
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."