Varaico: Literature-Extracted Genetic Variants

Gene:LEP
Variant:p.G152R

LEP

798 papers

RefSeq Summary

This gene encodes a protein that is secreted by white adipocytes into the circulation and plays a major role in the regulation of energy homeostasis. Circulating leptin binds to the leptin receptor in...

Pfam Domains

Leptinaa 23–167UCSCLeptin

Gene Aliases

HGNC Name

leptin

HGNC Previous Symbols

OBS; OB

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_000230.3
p.G152R
c.454G>C
Surrounding Variants
2 papers
NM_000230.3
p.G152R
c.454G>A
1 paper
NM_000230.3
p.G152W
c.454G>T
3 papers
NM_000230.3
p.G152E
c.455G>A
1 paper
NM_000230.3
p.Q151H
c.453G>C
2 papers
NM_000230.3
p.Q151H
c.453G>T
1 paper
NM_000230.3
p.Q151R
c.452A>G
2 papers
NM_000230.3
p.Q151delFs
c.453delG
3 papers
NM_000230.3
p.Q151*
c.451C>T
2 papers
NM_000230.3
p.S153P
c.457T>C
2 papers
NM_000230.3
p.S153fs
c.457_458fs
1 paper
NM_000230.3
p.S153fs
c.457_458fs
1 paper
NM_000230.3
p.L150L
c.450G>A
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