Varaico: Literature-Extracted Genetic Variants

Gene:LGMN
Variant:p.H301L

LGMN

99 papers

RefSeq Summary

This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for...

Pfam Domains

Peptidase_C13aa 29–286UCSCPeptidase C13 family
Legum_prodomaa 333–429UCSCLegumain, prodomain

Gene Aliases

HGNC Name

legumain

HGNC Previous Symbol

PRSC1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005606.7
p.H301L
c.902A>T
Surrounding Variants
1 paper
NM_005606.7
p.D303E
c.909C>G
1 paper
NM_005606.7
p.D303E
c.909C>A
1 paper
NM_005606.7
p.D309E
c.927T>G
1 paper
NM_005606.7
p.D309E
c.927T>A
1 paper
NM_005606.7
p.S291N
c.872G>A
2 papers
NM_005606.7
p.A290G
c.869C>G
1 paper
NM_005606.7
p.K289R
c.866A>G
1 paper
NM_005606.7
p.F283L
c.849T>G
1 paper
NM_005606.7
p.F283L
c.849T>A
1 paper
NM_005606.7
p.F283L
c.847T>C
1 paper
NM_005606.7
p.T322A
c.964A>G
1 paper
NM_005606.7
p.S328A
c.982T>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."