Varaico: Literature-Extracted Genetic Variants

LGR5

146 papers

RefSeq Summary

The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor ...

Pfam Domains

LRRNTaa 33–65UCSCLeucine rich repeat N-terminal domain

LRR_8aa 90–150UCSCLeucine rich repeat

LRR_4aa 210–256UCSCLeucine Rich repeats (2 copies)

LRR_8aa 328–386UCSCLeucine rich repeat

LRR_8aa 374–434UCSCLeucine rich repeat

Gene Aliases

HGNC Name

leucine rich repeat containing G protein-coupled receptor 5

HGNC Previous Symbols

GPR67; GPR49

Papers

RefSeq ID

Protein change

DNA change

1–12 of 258 variants

4 papers

NM_003667.4

p.L424V

c.1270C>G

4 papers

NM_003667.4

p.D532H

c.1594G>C

4 papers

NM_003667.4

p.P781A

c.2341C>G

3 papers

NM_003667.4

p.Q355R

c.1064A>G

3 papers

NM_003667.4

p.V484L

c.1450G>C

3 papers

NM_003667.4

p.Y839Y

c.2517C>T

2 papers

NM_003667.4

p.L30M

c.88T>A

2 papers

NM_003667.4

p.Q189*

c.565C>T

2 papers

NM_003667.4

p.L304F

c.912A>C

2 papers

NM_003667.4

p.L304F

c.912A>T

2 papers

NM_003667.4

p.P352S

c.1054C>T

2 papers

NM_003667.4

p.H383R

c.1148A>G