Varaico: Literature-Extracted Genetic Variants

LGR5

146 papers

RefSeq Summary

The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor ...

Pfam Domains

LRRNTaa 33–65UCSCLeucine rich repeat N-terminal domain

LRR_8aa 90–150UCSCLeucine rich repeat

LRR_4aa 210–256UCSCLeucine Rich repeats (2 copies)

LRR_8aa 328–386UCSCLeucine rich repeat

LRR_8aa 374–434UCSCLeucine rich repeat

Gene Aliases

HGNC Name

leucine rich repeat containing G protein-coupled receptor 5

HGNC Previous Symbols

GPR67; GPR49

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003667.4

p.G21R

c.61G>A

Surrounding Variants

1 paper

NM_003667.4

p.G21_G22ins0

c.63_65dupGGG

1 paper

NM_003667.4

p.T20I

c.59C>T

1 paper

NM_003667.4

p.Q17H

c.51G>C

1 paper

NM_003667.4

p.Q17H

c.51G>T

1 paper

NM_003667.4

p.L18del1

c.52_53delCTG

1 paper

NM_003667.4

p.Q17_A19delFs

c.51_57del7

1 paper

NM_003667.4

p.P25delFs

c.73_74delCC

1 paper

NM_003667.4

p.P25L

c.74C>T

1 paper

NM_003667.4

p.V14E

c.41T>A

1 paper

NM_003667.4

p.G28S

c.82G>A

1 paper

NM_003667.4

p.L30delFs

c.88delT

2 papers

NM_003667.4

p.L30M

c.88T>A