Varaico: Literature-Extracted Genetic Variants

LGR5

146 papers

RefSeq Summary

The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor ...

Pfam Domains

LRRNTaa 33–65UCSCLeucine rich repeat N-terminal domain

LRR_8aa 90–150UCSCLeucine rich repeat

LRR_4aa 210–256UCSCLeucine Rich repeats (2 copies)

LRR_8aa 328–386UCSCLeucine rich repeat

LRR_8aa 374–434UCSCLeucine rich repeat

Gene Aliases

HGNC Name

leucine rich repeat containing G protein-coupled receptor 5

HGNC Previous Symbols

GPR67; GPR49

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003667.4

p.S159R

c.477T>A

Surrounding Variants

1 paper

NM_003667.4

p.S159I

c.476G>T

1 paper

NM_003667.4

p.L161_L164del0

c.481_492del12

1 paper

NM_003667.4

p.H162Y

c.484C>T

1 paper

NM_003667.4

p.L164P

c.491T>C

1 paper

NM_003667.4

p.P154R

c.461C>G

1 paper

NM_003667.4

p.Y152C

c.455A>G

1 paper

NM_003667.4

p.Y152N

c.454T>A

1 paper

NM_003667.4

p.L167L

c.501G>C

1 paper

NM_003667.4

p.S151N

c.452G>A

1 paper

NM_003667.4

p.W168C

c.504G>C

1 paper

NM_003667.4

p.W168C

c.504G>T

1 paper

NM_003667.4

p.L169V

c.505C>G