Varaico: Literature-Extracted Genetic Variants

LGR5

146 papers

RefSeq Summary

The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor ...

Pfam Domains

LRRNTaa 33–65UCSCLeucine rich repeat N-terminal domain

LRR_8aa 90–150UCSCLeucine rich repeat

LRR_4aa 210–256UCSCLeucine Rich repeats (2 copies)

LRR_8aa 328–386UCSCLeucine rich repeat

LRR_8aa 374–434UCSCLeucine rich repeat

Gene Aliases

HGNC Name

leucine rich repeat containing G protein-coupled receptor 5

HGNC Previous Symbols

GPR67; GPR49

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003667.4

p.S186_L188delFs

c.557_563del7

Surrounding Variants

1 paper

NM_003667.4

p.S186L

c.557C>T

1 paper

NM_003667.4

p.S184G

c.550A>G

2 papers

NM_003667.4

p.Q189*

c.565C>T

1 paper

NM_003667.4

p.A181A

c.543T>G

1 paper

NM_003667.4

p.A190T

c.568G>A

1 paper

NM_003667.4

p.A190D

c.569C>A

1 paper

NM_003667.4

p.T192S

c.574A>T

1 paper

NM_003667.4

p.T192S

c.575C>G

1 paper

NM_003667.4

p.V179I

c.535G>A

1 paper

NM_003667.4

p.E176K

c.526G>A

1 paper

NM_003667.4

p.T175T

c.525A>T

1 paper

NM_003667.4

p.K197*

c.589A>T