Varaico: Literature-Extracted Genetic Variants

LGR5

146 papers

RefSeq Summary

The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor ...

Pfam Domains

LRRNTaa 33–65UCSCLeucine rich repeat N-terminal domain

LRR_8aa 90–150UCSCLeucine rich repeat

LRR_4aa 210–256UCSCLeucine Rich repeats (2 copies)

LRR_8aa 328–386UCSCLeucine rich repeat

LRR_8aa 374–434UCSCLeucine rich repeat

Gene Aliases

HGNC Name

leucine rich repeat containing G protein-coupled receptor 5

HGNC Previous Symbols

GPR67; GPR49

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003667.4

p.F288Y

c.863T>A

Surrounding Variants

1 paper

NM_003667.4

p.D290A

c.869A>C

1 paper

NM_003667.4

p.Q302*

c.904C>T

1 paper

NM_003667.4

p.Q302H

c.906A>C

2 papers

NM_003667.4

p.L304F

c.912A>C

2 papers

NM_003667.4

p.L304F

c.912A>T

1 paper

NM_003667.4

p.A315fs

c.943_944fs

1 paper

NM_003667.4

p.T319I

c.956C>T

1 paper

NM_003667.4

p.E320K

c.958G>A

1 paper

NM_003667.4

p.D323N

c.967G>A

1 paper

NM_003667.4

p.L324I

c.970T>A

1 paper

NM_003667.4

p.T325S

c.973A>T

1 paper

NM_003667.4

p.E331G

c.992A>G