Varaico: Literature-Extracted Genetic Variants

LGR5

146 papers

RefSeq Summary

The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor ...

Pfam Domains

LRRNTaa 33–65UCSCLeucine rich repeat N-terminal domain

LRR_8aa 90–150UCSCLeucine rich repeat

LRR_4aa 210–256UCSCLeucine Rich repeats (2 copies)

LRR_8aa 328–386UCSCLeucine rich repeat

LRR_8aa 374–434UCSCLeucine rich repeat

Gene Aliases

HGNC Name

leucine rich repeat containing G protein-coupled receptor 5

HGNC Previous Symbols

GPR67; GPR49

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003667.4

p.L335*

c.1004T>G

Surrounding Variants

1 paper

NM_003667.4

p.I340L

c.1018A>C

1 paper

NM_003667.4

p.S341L

c.1022C>T

1 paper

NM_003667.4

p.P344L

c.1031C>T

1 paper

NM_003667.4

p.Q345K

c.1033C>A

1 paper

NM_003667.4

p.C348G

c.1042T>G

2 papers

NM_003667.4

p.P352S

c.1054C>T

1 paper

NM_003667.4

p.L354_Q355ins6

c.1060_1064ins18

3 papers

NM_003667.4

p.Q355R

c.1064A>G

1 paper

NM_003667.4

p.L333Splc

c.998+4A>T

1 paper

NM_003667.4

p.E331G

c.992A>G

1 paper

NM_003667.4

p.T325S

c.973A>T

1 paper

NM_003667.4

p.L324I

c.970T>A