Varaico: Literature-Extracted Genetic Variants

LGR5

146 papers

RefSeq Summary

The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor ...

Pfam Domains

LRRNTaa 33–65UCSCLeucine rich repeat N-terminal domain

LRR_8aa 90–150UCSCLeucine rich repeat

LRR_4aa 210–256UCSCLeucine Rich repeats (2 copies)

LRR_8aa 328–386UCSCLeucine rich repeat

LRR_8aa 374–434UCSCLeucine rich repeat

Gene Aliases

HGNC Name

leucine rich repeat containing G protein-coupled receptor 5

HGNC Previous Symbols

GPR67; GPR49

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003667.4

p.H383R

c.1148A>G

Surrounding Variants

1 paper

NM_003667.4

p.Y387ins1

c.1160_1161insTTT

1 paper

NM_003667.4

p.E388K

c.1162G>A

1 paper

NM_003667.4

p.K390I

c.1169A>T

1 paper

NM_003667.4

p.L400V

c.1198C>G

1 paper

NM_003667.4

p.L400F

c.1198C>T

1 paper

NM_003667.4

p.S402L

c.1205C>T

1 paper

NM_003667.4

p.L403L

c.1207C>T

1 paper

NM_003667.4

p.K378R

c.1133A>G

1 paper

NM_003667.4

p.L376F

c.1126C>T

1 paper

NM_003667.4

p.C373delFs

c.1117_1118delTG

1 paper

NM_003667.4

p.S360delFs

c.1080delT

1 paper

NM_003667.4

p.L359R

c.1076T>G