Varaico: Literature-Extracted Genetic Variants

LGR5

146 papers

RefSeq Summary

The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor ...

Pfam Domains

LRRNTaa 33–65UCSCLeucine rich repeat N-terminal domain

LRR_8aa 90–150UCSCLeucine rich repeat

LRR_4aa 210–256UCSCLeucine Rich repeats (2 copies)

LRR_8aa 328–386UCSCLeucine rich repeat

LRR_8aa 374–434UCSCLeucine rich repeat

Gene Aliases

HGNC Name

leucine rich repeat containing G protein-coupled receptor 5

HGNC Previous Symbols

GPR67; GPR49

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003667.4

p.Q457H

c.1371G>T

Surrounding Variants

2 papers

NM_003667.4

p.Q457H

c.1371G>C

1 paper

NM_003667.4

p.S458R

c.1372A>C

1 paper

NM_003667.4

p.S458R

c.1374C>A

1 paper

NM_003667.4

p.S458R

c.1374C>G

1 paper

NM_003667.4

p.S461P

c.1381T>C

1 paper

NM_003667.4

p.L450*

c.1349T>A

1 paper

NM_003667.4

p.L450*

c.1349T>G

1 paper

NM_003667.4

p.L450delFs

c.1349delT

1 paper

NM_003667.4

p.H443delFs

c.1327delC

2 papers

NM_003667.4

p.S435L

c.1304C>T

1 paper

NM_003667.4

p.N432_L434del3

c.1294_1301del9

2 papers

NM_003667.4

p.D428N

c.1282G>A