Varaico: Literature-Extracted Genetic Variants

LGR5

146 papers

RefSeq Summary

The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor ...

Pfam Domains

LRRNTaa 33–65UCSCLeucine rich repeat N-terminal domain

LRR_8aa 90–150UCSCLeucine rich repeat

LRR_4aa 210–256UCSCLeucine Rich repeats (2 copies)

LRR_8aa 328–386UCSCLeucine rich repeat

LRR_8aa 374–434UCSCLeucine rich repeat

Gene Aliases

HGNC Name

leucine rich repeat containing G protein-coupled receptor 5

HGNC Previous Symbols

GPR67; GPR49

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_003667.4

p.V484L

c.1450G>C

Surrounding Variants

1 paper

NM_003667.4

p.G483E

c.1448G>A

1 paper

NM_003667.4

p.A481_S492del12

c.1441_1475del36

1 paper

NM_003667.4

p.K490N

c.1470G>C

1 paper

NM_003667.4

p.K490N

c.1470G>T

1 paper

NM_003667.4

p.S492insFs

c.1476dupT

1 paper

NM_003667.4

p.D504E

c.1512C>A

1 paper

NM_003667.4

p.D504E

c.1512C>G

1 paper

NM_003667.4

p.G512R

c.1534G>A

1 paper

NM_003667.4

p.G512R

c.1534G>C

1 paper

NM_003667.4

p.S461P

c.1381T>C

1 paper

NM_003667.4

p.S458R

c.1374C>A

1 paper

NM_003667.4

p.S458R

c.1374C>G