Varaico: Literature-Extracted Genetic Variants

LGR5

146 papers

RefSeq Summary

The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor ...

Pfam Domains

LRRNTaa 33–65UCSCLeucine rich repeat N-terminal domain

LRR_8aa 90–150UCSCLeucine rich repeat

LRR_4aa 210–256UCSCLeucine Rich repeats (2 copies)

LRR_8aa 328–386UCSCLeucine rich repeat

LRR_8aa 374–434UCSCLeucine rich repeat

Gene Aliases

HGNC Name

leucine rich repeat containing G protein-coupled receptor 5

HGNC Previous Symbols

GPR67; GPR49

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003667.4

p.M604I

c.1812G>T

Surrounding Variants

1 paper

NM_003667.4

p.M604I

c.1812G>A

1 paper

NM_003667.4

p.M604I

c.1812G>C

1 paper

NM_003667.4

p.M604T

c.1811T>C

1 paper

NM_003667.4

p.A601S

c.1801G>T

1 paper

NM_003667.4

p.A600S

c.1798G>T

1 paper

NM_003667.4

p.V612M

c.1834G>A

1 paper

NM_003667.4

p.A614V

c.1841C>T

1 paper

NM_003667.4

p.V582delFs

c.1745_1746delTT

1 paper

NM_003667.4

p.E632D

c.1896G>C

1 paper

NM_003667.4

p.E632D

c.1896G>T

1 paper

NM_003667.4

p.L570L

c.1708C>T

1 paper

NM_003667.4

p.V569L

c.1705G>C