Varaico: Literature-Extracted Genetic Variants

LGR5

146 papers

RefSeq Summary

The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor ...

Pfam Domains

LRRNTaa 33–65UCSCLeucine rich repeat N-terminal domain

LRR_8aa 90–150UCSCLeucine rich repeat

LRR_4aa 210–256UCSCLeucine Rich repeats (2 copies)

LRR_8aa 328–386UCSCLeucine rich repeat

LRR_8aa 374–434UCSCLeucine rich repeat

Gene Aliases

HGNC Name

leucine rich repeat containing G protein-coupled receptor 5

HGNC Previous Symbols

GPR67; GPR49

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003667.4

p.R662H

c.1985G>A

Surrounding Variants

1 paper

NM_003667.4

p.R662_Y668ins2

c.1986_2003dup18

1 paper

NM_003667.4

p.V666A

c.1997T>C

1 paper

NM_003667.4

p.K667N

c.2001A>C

1 paper

NM_003667.4

p.K667N

c.2001A>T

1 paper

NM_003667.4

p.T674S

c.2020A>T

1 paper

NM_003667.4

p.T674M

c.2021C>T

1 paper

NM_003667.4

p.L643*

c.1928T>A

1 paper

NM_003667.4

p.L690R

c.2069T>G

1 paper

NM_003667.4

p.L691Q

c.2072T>A

1 paper

NM_003667.4

p.E632D

c.1896G>C

1 paper

NM_003667.4

p.E632D

c.1896G>T

1 paper

NM_003667.4

p.L693F

c.2079G>C