Varaico: Literature-Extracted Genetic Variants

LGR5

146 papers

RefSeq Summary

The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor ...

Pfam Domains

LRRNTaa 33–65UCSCLeucine rich repeat N-terminal domain

LRR_8aa 90–150UCSCLeucine rich repeat

LRR_4aa 210–256UCSCLeucine Rich repeats (2 copies)

LRR_8aa 328–386UCSCLeucine rich repeat

LRR_8aa 374–434UCSCLeucine rich repeat

Gene Aliases

HGNC Name

leucine rich repeat containing G protein-coupled receptor 5

HGNC Previous Symbols

GPR67; GPR49

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003667.4

p.Y748D

c.2242T>G

Surrounding Variants

1 paper

NM_003667.4

p.G754_L756delFs

c.2262_2268del7

1 paper

NM_003667.4

p.M739_M740ins6

c.2215_2219ins18

1 paper

NM_003667.4

p.E757G

c.2270A>G

1 paper

NM_003667.4

p.H767H

c.2301C>T

1 paper

NM_003667.4

p.P720L

c.2159C>T

4 papers

NM_003667.4

p.P781A

c.2341C>G

1 paper

NM_003667.4

p.P714_L715insCA

c.2140_2144ins6

2 papers

NM_003667.4

p.C712F

c.2135G>T

1 paper

NM_003667.4

p.P710T

c.2128C>A

1 paper

NM_003667.4

p.L790I

c.2368T>A

1 paper

NM_003667.4

p.A697T

c.2089G>A

1 paper

NM_003667.4

p.E799D

c.2397A>C