Varaico: Literature-Extracted Genetic Variants

LGR5

146 papers

RefSeq Summary

The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor ...

Pfam Domains

LRRNTaa 33–65UCSCLeucine rich repeat N-terminal domain

LRR_8aa 90–150UCSCLeucine rich repeat

LRR_4aa 210–256UCSCLeucine Rich repeats (2 copies)

LRR_8aa 328–386UCSCLeucine rich repeat

LRR_8aa 374–434UCSCLeucine rich repeat

Gene Aliases

HGNC Name

leucine rich repeat containing G protein-coupled receptor 5

HGNC Previous Symbols

GPR67; GPR49

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003667.4

p.N816S

c.2447A>G

Surrounding Variants

1 paper

NM_003667.4

p.L815L

c.2445C>T

1 paper

NM_003667.4

p.L805V

c.2413C>G

1 paper

NM_003667.4

p.I801_F803del3

c.2401_2408del9

1 paper

NM_003667.4

p.E799D

c.2397A>C

1 paper

NM_003667.4

p.E799D

c.2397A>T

3 papers

NM_003667.4

p.Y839Y

c.2517C>T

1 paper

NM_003667.4

p.L790I

c.2368T>A

1 paper

NM_003667.4

p.R843T

c.2528G>C

2 papers

NM_003667.4

p.S848I

c.2543G>T

1 paper

NM_003667.4

p.M850R

c.2549T>G

4 papers

NM_003667.4

p.P781A

c.2341C>G

1 paper

NM_003667.4

p.I852V

c.2554A>G