Varaico: Literature-Extracted Genetic Variants

Gene:LIMK1
Variant:p.I182F

LIMK1

139 papers

RefSeq Summary

There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc ...

Pfam Domains

LIMaa 25–80UCSCLIM domain
LIMaa 84–142UCSCLIM domain
PDZaa 165–255UCSCPDZ domain
PK_Tyr_Ser-Thraa 339–604UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

LIM domain kinase 1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002314.4
p.I182F
c.544A>T
Surrounding Variants
1 paper
NM_002314.4
p.H186H
c.558C>T
1 paper
NM_002314.4
p.G187D
c.560G>A
1 paper
NM_002314.4
p.R176insFs
c.527dupG
2 papers
NM_002314.4
p.G190A
c.569G>C
1 paper
NM_002314.4
p.E194A
c.581A>C
1 paper
NM_002314.4
p.V199I
c.595G>A
2 papers
NM_002314.4
p.R200H
c.599G>A
1 paper
NM_002314.4
p.P145P
c.435C>T
1 paper
NM_002314.4
p.Y133H
c.397T>C
1 paper
NM_002314.4
p.C114R
c.340T>C
1 paper
NM_002314.4
p.C111C
c.333C>T
1 paper
NM_002314.4
p.K103T
c.308A>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."