Varaico: Literature-Extracted Genetic Variants

LIN28A

79 papers

RefSeq Summary

This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded prote...

Pfam Domains

CSDaa 40–112UCSC'Cold-shock' DNA-binding domain

zf-CCHCaa 137–154UCSCZinc knuckle

Lin-28A-like_zf-CCHC_2aa 158–189UCSCLin-28A-like, second zinc knuckle

Gene Aliases

HGNC Name

lin-28 RNA binding posttranscriptional regulator A

HGNC Previous Symbol

LIN28

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024674.6

p.P205P

c.615G>A

Surrounding Variants

1 paper

NM_024674.6

p.P205L

c.614C>T

1 paper

NM_024674.6

p.H199R

c.596A>G

1 paper

NM_024674.6

p.H199N

c.595C>A

2 papers

NM_024674.6

p.H199Y

c.595C>T

1 paper

NM_024674.6

p.R192R

c.576A>G

7 papers

NM_024674.6

p.R192G

c.574C>G

1 paper

NM_024674.6

p.Y190Y

c.570C>T

1 paper

NM_024674.6

p.T189T

c.567C>G

3 papers

NM_024674.6

p.T189I

c.566C>T

1 paper

NM_024674.6

p.P188Q

c.563C>A

1 paper

NM_024674.6

p.G186E

c.557G>A

2 papers

NM_024674.6

p.P182L

c.545C>T