Varaico: Literature-Extracted Genetic Variants

Gene:LPL
Variant:p.I35N

LPL

1,048 papers

RefSeq Summary

LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor f...

Pfam Domains

Lipaseaa 17–338UCSCLipase
PLATaa 343–463UCSCPLAT/LH2 domain

Gene Aliases

HGNC Name

lipoprotein lipase

HGNC Previous Symbol

LIPD

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_000237.3
p.I35N
c.104T>A
Surrounding Variants
49 papers
NM_000237.3
p.D36N
c.106G>A
1 paper
NM_000237.3
p.D36G
c.107A>G
3 papers
NM_000237.3
p.F34Y
c.101T>A
1 paper
NM_000237.3
p.F34S
c.101T>C
1 paper
NM_000237.3
p.I37V
c.109A>G
1 paper
NM_000237.3
p.D33insFs
c.98_99insTG
12 papers
NM_000237.3
p.D33V
c.98A>T
1 paper
NM_000237.3
p.I37M
c.111C>G
1 paper
NM_000237.3
p.E38del1
c.112_113delGAA
1 paper
NM_000237.3
p.R32_D33insFs
c.96_97insGT
1 paper
NM_000237.3
p.R32R
c.96A>G
6 papers
NM_000237.3
p.E38K
c.112G>A
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