Varaico: Literature-Extracted Genetic Variants

LRCH4

56 papers

RefSeq Summary

This gene encodes a protein that contains leucine-rich repeats (LRR) at its amino terminus and that is known to be involved in ligand binding. The carboxyl terminus may act as a membrane anchor. Ident...

Pfam Domains

LRR_8aa 70–126UCSCLeucine rich repeat

LRR_8aa 137–194UCSCLeucine rich repeat

CHaa 535–650UCSCCalponin homology (CH) domain

Gene Aliases

HGNC Name

leucine rich repeats and calponin homology domain containing 4

HGNC Previous Symbol

LRN

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002319.5

p.V645G

c.1934T>G

Surrounding Variants

1 paper

NM_002319.5

p.G646A

c.1937G>C

1 paper

NM_002319.5

p.V642M

c.1924G>A

1 paper

NM_002319.5

p.P651S

c.1951C>T

1 paper

NM_002319.5

p.A638V

c.1913C>T

1 paper

NM_002319.5

p.L628F

c.1882C>T

1 paper

NM_002319.5

p.K599N

c.1797G>T

1 paper

NM_002319.5

p.K599N

c.1797G>C

1 paper

NM_002319.5

p.A591V

c.1772C>T

1 paper

NM_002319.5

p.A574T

c.1720G>A

1 paper

NM_002319.5

p.R545H

c.1634G>A

1 paper

NM_002319.5

p.P535T

c.1603C>A

1 paper

NM_002319.5

p.R530Q

c.1589G>A