Varaico: Literature-Extracted Genetic Variants

LRCH4

56 papers

RefSeq Summary

This gene encodes a protein that contains leucine-rich repeats (LRR) at its amino terminus and that is known to be involved in ligand binding. The carboxyl terminus may act as a membrane anchor. Ident...

Pfam Domains

LRR_8aa 70–126UCSCLeucine rich repeat

LRR_8aa 137–194UCSCLeucine rich repeat

CHaa 535–650UCSCCalponin homology (CH) domain

Gene Aliases

HGNC Name

leucine rich repeats and calponin homology domain containing 4

HGNC Previous Symbol

LRN

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002319.5

p.P535T

c.1603C>A

Surrounding Variants

1 paper

NM_002319.5

p.R530Q

c.1589G>A

1 paper

NM_002319.5

p.R545H

c.1634G>A

1 paper

NM_002319.5

p.A574T

c.1720G>A

1 paper

NM_002319.5

p.A591V

c.1772C>T

1 paper

NM_002319.5

p.P497R

c.1490C>G

1 paper

NM_002319.5

p.K599N

c.1797G>T

1 paper

NM_002319.5

p.K599N

c.1797G>C

1 paper

NM_002319.5

p.P476P

c.1428T>C

1 paper

NM_002319.5

p.N455Y

c.1363A>T

1 paper

NM_002319.5

p.L628F

c.1882C>T

1 paper

NM_002319.5

p.W425*

c.1275G>A

1 paper

NM_002319.5

p.W425*

c.1274G>A