Varaico: Literature-Extracted Genetic Variants

LRIG2

88 papers

RefSeq Summary

This gene encodes a transmembrane protein containing leucine-rich repeats and immunoglobulin-like domains. The encoded protein promotes epidermal growth factor signalling, resulting in increased proli...

Pfam Domains

LRR_8aa 144–195UCSCLeucine rich repeat

LRR_8aa 240–299UCSCLeucine rich repeat

LRR_8aa 289–347UCSCLeucine rich repeat

LRR_8aa 311–371UCSCLeucine rich repeat

LRR_8aa 386–445UCSCLeucine rich repeat

Gene Aliases

HGNC Name

leucine rich repeats and immunoglobulin like domains 2

HGNC Alias Symbol

KIAA0806

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_014813.3

p.I852F

c.2554A>T

Surrounding Variants

1 paper

NM_014813.3

p.G894S

c.2680G>A

1 paper

NM_014813.3

p.G894Splc

c.2680+9T>G

1 paper

NM_014813.3

p.I840V

c.2518A>G

1 paper

NM_014813.3

p.S839N

c.2516G>A

1 paper

NM_014813.3

p.E836G

c.2507A>G

2 papers

NM_014813.3

p.E836*

c.2506G>T

1 paper

NM_001312686.2

p.I723_V724insGGA

c.2167_2171ins9

1 paper

NM_014813.3

p.V818A

c.2453T>C

1 paper

NM_001312686.2

p.V709A

c.2126T>C

2 papers

NM_014813.3

p.V806A

c.2417T>C

2 papers

NM_014813.3

p.E799*

c.2395G>T

1 paper

NM_014813.3

p.T765I

c.2294C>T