Varaico: Literature-Extracted Genetic Variants

Gene:LRR1
Variant:p.S378A

LRR1

70 papers

RefSeq Summary

The protein encoded by this gene contains a leucine-rich repeat (LRR). It specifically interacts with TNFRSF9/4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily. Overexpression o...

Pfam Domains

PH_LRR1aa 1–123UCSCLRR1 pleckstrin homology domain
LRR_4aa 177–219UCSCLeucine Rich repeats (2 copies)

Gene Aliases

HGNC Name

leucine rich repeat protein 1

HGNC Previous Symbol

PPIL5

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_152329.4
p.S378A
c.1132T>G
Surrounding Variants
1 paper
NM_152329.4
p.A380V
c.1139C>T
1 paper
NM_152329.4
p.G370V
c.1109G>T
1 paper
NM_152329.4
p.V386A
c.1157T>C
1 paper
NM_152329.4
p.D387Y
c.1159G>T
1 paper
NM_152329.4
p.T392A
c.1174A>G
1 paper
NM_152329.4
p.S398F
c.1193C>T
1 paper
NM_152329.4
p.F400L
c.1198T>C
1 paper
NM_152329.4
p.F400L
c.1200C>A
1 paper
NM_152329.4
p.F400L
c.1200C>G
1 paper
NM_152329.4
p.L403Q
c.1208T>A
1 paper
NM_152329.4
p.C405G
c.1213T>G
1 paper
NM_152329.4
p.D350G
c.1049A>G
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