Varaico: Literature-Extracted Genetic Variants

LRRC3B

29 papers

RefSeq Summary

The protein encoded by this gene is a tumor suppressor, with lowered expression levels found in gastric, renal, colorectal, lung, and breast cancer tissues. The promoter of this gene is frequently hyp...

Pfam Domains

LRRNTaa 33–63UCSCLeucine rich repeat N-terminal domain

LRR_8aa 64–114UCSCLeucine rich repeat

LRR_1aa 114–136UCSCLeucine Rich Repeat

Gene Aliases

HGNC Name

leucine rich repeat containing 3B

HGNC Alias Symbol

LRP15

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_052953.4

p.I25T

c.74T>C

Surrounding Variants

1 paper

NM_052953.4

p.S13P

c.37T>C

1 paper

NM_052953.4

p.R10P

c.29G>C

1 paper

NM_052953.4

p.C40W

c.120T>G

1 paper

NM_052953.4

p.S41C

c.122C>G

1 paper

NM_052953.4

p.G44V

c.131G>T

1 paper

NM_052953.4

p.A53G

c.158C>G

1 paper

NM_052953.4

p.F84S

c.251T>C

1 paper

NM_052953.4

p.K85E

c.253A>G

1 paper

NM_052953.4

p.N94K

c.282C>A

1 paper

NM_052953.4

p.N94K

c.282C>G

1 paper

NM_052953.4

p.N98I

c.293A>T

1 paper

NM_052953.4

p.H106Y

c.316C>T